🌿 Seed:

• Linalool: A terpene alcohol with sedative, anticonvulsant, and blood sugar-lowering effects.

• Geranyl acetate: Smooth muscle relaxant; aids gut motility.

• Coumarins & flavonoids: Antioxidant, anti-lipidemic, modulate liver detox enzymes.

• Minerals: Iron, magnesium, manganese, and a rare, gentle source of vitamin K.

🌿 Leaf (Cilantro):

• Vitamin C, A, and K1: Potent antioxidant triad; supports collagen, liver, and blood.

• Carotenoids: Eye and immune protection.

• Chelation co-factors: Substances suspected to bind certain metals, supporting detox.

• Volatile oils: High turnover — very active, very fleeting.

2. 🌡️ Blood Sugar & Insulin Mimicry

• A 1999 study found coriander seed extract stimulated insulin secretion 5.7x over baseline in beta cell lines.

• In diabetic rats, coriander extract restored beta cells, improved fasting glucose, triglycerides, and serum insulin.

• A 2022 human study showed coriander reduced fasting glucose, LDL, triglycerides, and markers of oxidative stress.

• Mechanism: via AMPK activation, enhanced glucose uptake, and pancreatic regeneration.

Coriander acts as both insulin sensitizer and secretagogue — one of the rare herbs to do both.

3. 🧐 Memory, Mood, and Neuroinflammation

• Coriander essential oil improved scopolamine-induced memory loss in zebrafish and mice.

• Flavonoids in both seed and leaf reduced oxidative stress in the hippocampus.

• Terpenes like linalool and borneol have GABA-mimetic effects, reducing anxiety and improving sleep.

• Animal models show coriander protects against seizure, neuroinflammation, and degenerative disorders.

This is a full-spectrum gut-brain herb: vagus modulation, cortisol dampening, cognitive protection.

4. 🦠 Liver & Detox Enzymes

• Coriander stimulates bile production and liver phase I & II detox enzymes, including glutathione-S-transferase (GST).

• The seed’s oils support microsomal oxidation, breaking down lipid-soluble toxins.

• Cilantro (leaf) contains natural chelation support via polyphenols and flavonoids.

This is not a hammer chelator. It’s a whispering herb that assists the body’s existing detox gears.

5. 🪜 Microbiome Interactions

• Coriander oils inhibit Salmonella, E. coli, and gas-forming gut pathogens.

• Acts as a prebiotic modulator: helping stabilize microbial populations after dysbiosis.

• Stimulates bile acid flow, helping reshape gut microbial terrain.

Digestive calm + microbial diplomacy = coriander’s real genius.